◀ Back to SMC5

KLF4 — SMC5

Text-mined interactions from Literome

Liu et al., J Biol Chem 2003 : The aims of the present studies were to : 1 ) determine the role of the SM alpha-actin TCE in vivo through mutagenesis studies in transgenic mice and 2 ) further characterize the possible role and mechanisms by which the TCE binding factor GKLF/KLF4 induces repression of SMC marker genes in various SMC model systems in vitro
Liu et al., J Biol Chem 2005 : Moreover, previous studies have demonstrated that the Kruppel-like transcription factor ( KLF) 4 potently represses the expression of multiple SMC genes ... The goals of the present studies were to determine the molecular mechanisms by which KLF4 represses expression of SMC genes and whether it contributes to PDGF-BB induced suppression of these genes ... Results demonstrated that KLF4 markedly repressed both myocardin induced activation of SMC genes and expression of myocardin