Sanz-Moreno et al., Curr Biol 2012
(Neoplasm Invasiveness) :
Elongated mesenchymal migration of cancer cells is driven by Rac1 activation mediated by the adaptor NEDD9 and the exchange factor DOCK3
Ding et al., J Biol Chem 2013
(Wnt Signaling Pathway) :
Consistent with the role of Dvl in both Wnt/ß-catenin and Wnt/planar cell polarity signaling, NEDD4L regulates the cellular ß-catenin level and Rac1 , RhoA, and JNK activities