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BCL10 — SRC
Text-mined interactions from Literome
Karni et al., Oncogene 1999
(Cell Transformation, Neoplastic) :
Using a construct in which the promoter of Bcl-X, which possesses putative Stat3 sites, is tethered to the luciferase reporter gene, we show that inhibition of
Src activity or expression
induces a decline in
Bcl-X expression ... We also show that the expression of activated
Src induces activation of the
Bcl-X promoter ... Furthermore, these results also suggest that
Src positively
regulates Bcl-XL expression via Stat3 activation and thus acts not only as a potent mitogenic signaling element, but also as an anti-apoptotic signaling protein
Ogata et al., Hypertension 2003
:
The experiments with KI mutants for various tyrosine kinases revealed that
c-Src and Pyk2 ( but not JAK1, Jak2, Syk, and Tec ) are
involved in ET-1 induced upregulation of
Bcl-xL expression