Gene interactions and pathways from curated databases and text-mining

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CDH1 — IL18

Text-mined interactions from Literome

Jiang et al., Proteomics 2003 (Neoplasm Metastasis...) : The results demonstrated that ectopically expressed IL-18 promoted cell motility in vitro and down-regulated E-cadherin expression of PLA801C transfectants, while IL-18 antisense remarkably decreased cell invasion potency in vitro and notably increased E-cadherin expression of PLA801D transfectants, indicating that IL-18 might play a role in metastasis by inhibiting E-cadherin expression
Bani-Hani et al., Kidney Int 2009 (Fibrosis) : Similarly, the HK-2 cells exhibited increased alpha-smooth muscle actin expression and collagen production, and decreased E-cadherin expression in response to IL-18 stimulation without alterations in TNF-alpha or TGF-beta1 activity
Chen et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2009 : [ The effect of IL-18 on E-cadherin expression and its possible intracellular pathway in HK-2 cells ]
Jee et al., J Korean Med Sci 2012 (Stomach Neoplasms) : Prostaglandin E ( 2 ) and interleukin-1ß reduce E-cadherin expression by enhancing snail expression in gastric cancer cells