Gene interactions and pathways from curated databases and text-mining

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GPI — MET

Text-mined interactions from Literome

Funasaka et al., Cancer Res 2007 (Fibrosarcoma...) : This study identifies that MET in HT1080 human lung fibrosarcoma cells was initiated by down-regulation of the housekeeping gene product/cytokine PGI/AMF , and the results depicted here suggest a novel therapeutic target/modality for mesenchymal cancers
Funasaka et al., Cancer Res 2009 (Breast Neoplasms) : Taken together, the results show the involvement of PGI/AMF in both EMT and MET : overexpression of PGI/AMF induces EMT in normal breast epithelial cells and reduction of PGI/AMF expression led to MET in aggressive breast cancer cells
Niinaka et al., Cancer Res 2010 (Lung Neoplasms...) : Silencing of AMF/PGI induced MET , in which upregulation of E-cadherin and cytokeratins, as well as downregulation of vimentin, were noted
Przygodzki et al., J Physiol Biochem 2012 : Our present study was aimed at verifying whether the increased production of PGI ( 2 ), a vasodilating prostanoid, in response to MNA, its metabolite N-methyl-2-pyridone-5-carboxamide (Met2PY) , and nicotinamide may be reproduced under in vitro conditions
Fantone et al., Biochim Biophys Acta 1984 : In this study we have examined the effects of PGEs and PGI2 on f-Met-Leu-Phe- and phorbol-myristate-acetate induced rat neutrophil membrane potential changes using an optical probe of membrane potential 3,3-dipropylthiodicarbocyanine iodide