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NFKB1 — PDGFB
Text-mined interactions from Literome
Rauch et al., FEBS Lett 2000
:
The present study investigates the role of Akt in the
activation of
NF-kappa B by tumor necrosis factor-alpha ( TNF alpha, 10 ng/ml ) and
PDGF-BB ( 20 ng/ml ) in human vascular smooth muscle cells ( SMC ), skin and foreskin fibroblasts
Li et al., Zhonghua Bing Li Xue Za Zhi 2001
:
Ang II is effective to activate
NF-kappa B through a pathway dependent on NIK, IKK alpha and IKK beta, and
induces PDGF-B transcription in the endothelial cell line ECV304
Li et al., Chin Med J (Engl) 2002
:
Effect of
NF-kappaB on the induction of
PDGF-B transcription by angiotensin II in the ECV304 cell line
Eng et al., Microvasc Res 2003
:
Further supporting NF-kappaB regulation of PDGF-B, activation of
NF-kappaB by interleukin (IL)-1beta
resulted in increased
PDGF-B transcript levels
Yin et al., Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2001
:
To investigate the signal transduction pathway of
NF-kB activated by minimally modified low density lipoprotein ( mm-LDL ) in endothelial cells and the
effect of NF-kB on
platelet derived growth factor b (PDGFb) mRNA expression ... In addition, endothelial cells were transfected using PDGFb promoter-luciferase for reporter gene analysis or transfected with mut-NIK for slot blot analysis to study the
effect of
NF-kB on
PDGFb mRNA expression
van Steensel et al., Invest Ophthalmol Vis Sci 2010
(Graves Ophthalmopathy) :
PDGF-BB induced
NF-kappaB activity in orbital fibroblasts, and both NF-kappaB inhibitors and imatinib mesylate reduced PDGF-BB induced cytokine production
Marumo et al., Circulation 1997
:
Gel mobility shift assay revealed that PDGF-AB increased the binding activity of NF-kappaB, which contained predominantly the p50/p65 heterodimer in nuclear extracts from HSMCs. Superoxide dismutase as well as iodonium diphenyl, Ro 31-8220, and wortmannin attenuated
PDGF-AB induced
activation of
NF-kappaB and expression of MCP-1 mRNA