Zhang et al., Oncogene 2006
:
p53 negatively regulates the expression of FAT10 , a gene upregulated in various cancers
Peng et al., J Mol Cell Cardiol 2013
(Myocardial Ischemia) :
Lentiviral mediated overexpression of FAT10 in NRCM reduced p53 ( TP53 ) and its target miR-34a levels, while BCL2 level, a target of miR-34a, was increased and BAX level, a pro-apoptotic protein, was reduced