Ritchie et al., Oncogene 1999
:
Inhibition of the JAK/STAT pathway revealed that JAK/STAT signaling plays an insignificant role in conformational modulation of p53 and apoptosis suppression
Chen et al., Proc Natl Acad Sci U S A 1999
(Burkitt Lymphoma...) :
We provide evidence that Zta up-regulation of p53 leads to p53 mediated interference with JAK/STAT activation of Qp
Lee et al., Int J Cancer 2008
(Carcinoma, Squamous Cell...) :
Greater modulation among HNSCC lines expressing low wt p53 than those over expressing mt p53 protein suggested that decreased p53 expression might enhance activation of NF-kappaB, STAT3 and BCL-XL
Vaughan et al., Arch Biochem Biophys 2012
:
p53 mutants induce transcription of NF-?B2 in H1299 cells through CBP and STAT binding on the NF-?B2 promoter and gain of function activity