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EPHB2 — RGS4

Text-mined interactions from Literome

Leone et al., J Neurochem 2000 (Neuroblastoma) : Activation of extracellular signal regulated kinase ( ERK ) and Akt by human serotonin 5-HT(1B) receptors in transfected BE ( 2 ) -C neuroblastoma cells is inhibited by RGS4
Semplicini et al., J Hypertens 2006 (Hypertension) : Reduced expression of regulator of G-protein signaling 2 ( RGS2 ) in hypertensive patients increases calcium mobilization and ERK1/2 phosphorylation induced by angiotensin II
Hu et al., Am J Physiol Cell Physiol 2009 : Upregulation of RGS4 expression by IL-1beta in colonic smooth muscle is enhanced by ERK1/2 and p38 MAPK and inhibited by the PI3K/Akt/GSK3beta pathway ... These findings suggest that ERK1/2 and p38 MAPK enhance IL-1beta induced upregulation of RGS4 ; the effect of ERK1/2 reflects its ability to promote IKK2 phosphorylation and increase NF-kappaB activity
Schwendt et al., Psychopharmacologia 2012 (MAP Kinase Signaling System) : RGS4 overexpressed in the dSTR coimmunoprecipitated with mGluR5 receptors and suppressed both behavioral activity and phospho-ERK levels induced by DHPG ... RGS4 overexpression or the mGluR5 antagonist, 3- ( ( 2-methyl-4-thiazolyl ) ethynyl ) pyridine ( MTEP ), attenuated amphetamine induced phospho-ERK ( but not phospho-Akt ) levels