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AQP1 — PGR

Text-mined interactions from Literome

Cerdà et al., Fish Physiol Biochem 2013 : Investigations into the regulation of Aqp1ab during oogenesis indicate that the mRNA and protein product are highly accumulated during early oocyte growth, possibly through the transcriptional activation of the aqp1ab promoter by the classical nuclear progesterone receptor and perhaps by Sry related high mobility group [ HMG ] -box ( Sox ) transcription factors
Zapater et al., Dev Biol 2013 : Functional characterization of wild-type and mutated aqp1ab promoter constructs, using mammalian cells and Xenopus laevis oocytes, demonstrated that aqp1ab transcription is initiated by the Pgr , which is activated by the progestin 17a,20ß-dihydroxy-4-pregnen-3-one ( 17,20ß-P ), the natural ligand of the seabream Pgr ... In vitro incubation of seabream primary ovarian explants with the follicle stimulating hormone or 17,20ß-P confirmed that progestin activated Pgr enhanced Aqp1ab synthesis via the aqp1ab promoter