Gene interactions and pathways from curated databases and text-mining

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CFL1 — SRC

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Yoo et al., Oncogene 2010 : Together, these results suggest a novel mechanism by which cofilin is regulated by v-Src through tyrosine phosphorylation at Y68 that triggers the degradation of cofilin through ubiquitination-proteosome pathway and consequently inhibits cofilin activity in reducing cellular F-actin contents and cell spreading
Liao et al., Endocrinology 2010 : Inhibition of JNK1/2, c-Src , and phosphatidylinositol 3-kinase/Akt suppressed VEGF induced stress fiber formation and cofilin-1 phosphorylation