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E2F1 — MYLIP

Text-mined interactions from Literome

Scherr et al., Nucleic Acids Res 2007 : Furthermore, protein expression of E2F-1, a known miR-20 target, is enhanced by lentivirally expressed anti-miR-20 antagomirs in a dose dependent manner, whereas over-expression of miR-20a reduces E2F-1 levels
Petrocca et al., Cancer Cell 2008 (Adenocarcinoma...) : In turn, miR-106b and miR-93 regulate E2F1 expression, establishing a miRNA directed negative feedback loop
Aguda et al., Proc Natl Acad Sci U S A 2008 (Neoplasms) : In return, E2F and Myc induce the transcription of miR-17-92 , thus forming a negative feedback loop in the interaction network
Pulikkan et al., Blood 2010 (Leukemia, Myeloid, Acute) : We further show that E2F1 binds to the miR-223 promoter in AML blast cells and inhibits miR-223 transcription, suggesting that E2F1 is a transcriptional repressor of the miR-223 gene in AML
Zauli et al., Clin Cancer Res 2011 (Leukemia) : miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells
Dar et al., J Biol Chem 2011 (Melanoma...) : Overexpression of miR-205 in melanoma cells reduced E2F1 and E2F5 protein levels
Lizé et al., Cell cycle (Georgetown, Tex.) 2011 : Instead of p53, however, the cell cycle regulatory transcription factor E2F1 induces miR-449
Noguchi et al., J Biol Chem 2012 (Melanoma) : The ectopic expression of miR-203 in melanoma cells reduced the levels of E2F3a, E2F3b , and ZBP-89 protein expression
Yan et al., PloS one 2012 : In turn, E2F is inhibited by miR449 through regulating different transcripts, thus forming negative feedback loops in the interaction network
Fu et al., Zhonghua Gan Zang Bing Za Zhi 2012 (Carcinoma, Hepatocellular...) : The protein levels of cyclinD1, cyclinG1, and E2F1 were significantly reduced by both miR-338-3p and miR-551b ( P less than 0.001 )
El Tayebi et al., Biochem Biophys Res Commun 2013 (Carcinoma, Hepatocellular...) : E2F-1, c-MYC, and miR-17-5p is a triad of two regulatory loops : a negative and a positive loop, where c-MYC induces the expression of E2F-1 that induces the expression of miR-17-5p which in turn reverses the expression of E2F-1 to close the loop
Noguchi et al., Mol Ther 2013 (Melanoma) : Exogenous miR-205BP/S3 suppressed the protein expression levels of E2F1 and VEGF, which are validated targets of miR-205-5p, and BCL2, a transcribed molecule of E2F1, as did Pre-miR-205, used as a miR-205 mimic having the wild-type sequence