Mouneimne et al., Cancer Cell 2009
:
In this issue of Cancer Cell, Evdokimova et al. demonstrate that YB-1 regulates epithelial-mesenchyme transition (EMT) by inducing cap independent translation of mRNAs encoding EMT promoting factors and suppressing cap dependent translation of mRNAs encoding growth promoting factors
Evdokimova et al., Cancer Cell 2009
(Breast Neoplasms...) :
Enforced expression of YB-1 in noninvasive breast epithelial cells induced an epithelial-mesenchymal transition (EMT) accompanied by enhanced metastatic potential and reduced proliferation rates