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CSN3 — TNF
Text-mined interactions from Literome
Hong et al., FEBS Lett 2001
:
CSN3 interacts with IKKgamma and
inhibits TNF- but not IL-1 induced NF-kappaB activation
Van Lint et al., J Biol Chem 1992
:
Chromatography on Mono Q resolved multiple kinase peaks with each substrate tested and moreover revealed a
TNF mediated
casein kinase-2 activation in both cell lines, measurable with the specific RRREEESEEE peptide or with the G peptide
Kim et al., Eur J Pharmacol 2004
(Ion Channel Gating) :
TNF-alpha and apigenin, a
casein kinase2 ( CK2 ) inhibitor , showed decreased CK2 phosphorylation and increased PTEN phosphorylation, which were reversed by KR-31378
Ip et al., Endocrinology 1992
:
In optimal lactogenic medium,
TNF alpha ( 10-10,000 U/ml )
inhibited casein production ... At low concentrations ( approximately 5 U/ml ),
TNF alpha
stimulated casein production in parallel to its stimulation of morphological differentiation, although not to the same extent as in medium containing optimal levels of EGF
Mikkelsen et al., J Agric Food Chem 2005
:
kappa-Casein, glycomacropeptide, and lactoferrin differentially affected cytokine production by DC :
kappa-casein significantly
inhibited production of
TNF-alpha , IL-10, -12, -6, and -1beta, independent of sialic acid, whereas less marked effects of glycomacropeptide and lactoferrin were seen
Asare et al., Thromb Haemost 2013
:
This was paralleled by an increased NF-?B-driven upregulation of atherogenic chemokines and adhesion molecules, as measured by qPCR and flow cytometry, and translated into an enhanced arrest of THP-1 monocytes on
TNF-a stimulated ,
CSN5 depleted HUVECs
Watanabe et al., J Leukoc Biol 1993
:
Increasing the dietary alpha-linolenate ( 18 : 3n - 3 ) /linoleate ( 18 : 2n - 6 ) ratio results in an increase in lipopolysaccharide (LPS) stimulated
tumor necrosis factor (TNF) production in mouse resident and
casein induced peritoneal macrophages [ 3 ]
Guesdon et al., J Biol Chem 1993
:
Interleukin 1 and
tumor necrosis factor stimulate two novel protein kinases that phosphorylate the heat shock protein hsp27 and
beta-casein
Wong et al., Immunol Cell Biol 1996
:
While
beta-casein had no significant effects on IFN gamma production by ovine blood lymphocytes, and
TNF alpha production and MCH Class II antigen expression by ovine bronchoalveolar macrophages, it enhanced IL-1 beta production by the macrophages, beta-casein also had no influence on bovine NK cell activity against a virally infected cell line