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IL8 — RHOA

Text-mined interactions from Literome

Schmeck et al., Biochem Pharmacol 2006 : Activation of RhoA , Rac1 and Cdc42 ( CNF1 ), but not of RhoA alone ( CNF ( Y ) ), enhanced Listeria dependent IL-8 release significantly
Perez et al., Am J Physiol Lung Cell Mol Physiol 2007 (Cystic Fibrosis...) : Continuous inhibition of CFTR-Cl ( - ) conductance for 3-5 days resulted in significant increase in IL-8 secretion at basal ( P = 0.006 ) and in response to 10 ( 9 ) Pseudomonas ( P = 0.0001 ), a fourfold decrease in Smad3 expression ( P = 0.02 ), a threefold increase in RhoA expression, and increased NF-kappaB nuclear translocation upon TNF-alpha/IL-1beta stimulation ( P < 0.000001 )
Petreaca et al., Mol Biol Cell 2007 : Furthermore, inhibition of the VEGFR abolishes RhoA activation by IL-8/CXCL8 , and gap formation, suggesting a mechanism whereby VEGFR2 transactivation mediates IL-8/CXCL8 induced permeability
Liang et al., Zhonghua Yi Xue Za Zhi 2011 (Arthritis, Rheumatoid) : Inhibition of RhoA and ROCK with a specific inhibitor inhibited the secretion of IL-8 , RANTES and MCP-2 in PG-induced RA FLS