◀ Back to SMAD2
INHBA — SMAD2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Zhang et al., Diabetologia 1999
:
Activin A induced serine-phosphorylation and the subsequent accumulation of the
Smad2 in nuclei
Schmierer et al., J Biol Chem 2003
:
Activin a signaling
induces Smad2 , but not Smad3, requiring protein kinase a activity in granulosa cells from the avian ovary
Pholnukulkit et al., Biosci Biotechnol Biochem 2003
(Colonic Neoplasms) :
Activin A induces phosphorylation of
Smad2 but not complex formation of Smad2 with Smad4 in human colon cancer cell line HT-29
Bernard et al., Mol Endocrinol 2004
:
Activin A- and ALK4T206D stimulated transcription of the FSHbeta gene were significantly
attenuated by the depletion of either
SMAD2 or SMAD3
Coutts et al., Dev Biol 2008
:
Activin A increased and follistatin decreased phosphorylation of SMAD2/3 in vitro, and activin
increased SMAD2 and decreased KITLG mRNA expression
Simon et al., Neoplasia (New York, N.Y.) 2009
(Neuroblastoma...) :
Activin A induced
Smad2 phosphorylation and PCC proliferation, but only in the presence of fetal bovine serum ( FBS )
Stoikos et al., Hum Reprod 2010
(Endometriosis...) :
Activin A activated
Smad2 in a concentration dependent manner which was blocked by an activin receptor inhibitor ( SB431542 )
Zhang et al., J Int Med Res 2010
(Glioblastoma) :
Activin A also
induced up-regulation of
p-SMAD2/3 in a dose dependent manner
Wang et al., Cell Signal 2012
:
Activin A induction of murine and ovine follicle stimulating hormone ß transcription is
SMAD dependent and TAK1 ( MAP3K7 ) /p38 MAPK independent in gonadotrope-like cells
Shimizu et al., Genes Cells 1998
:
Activin A preferentially
induced the nuclear translocation of Smad3 in HaCaT cells, whereas TGF-beta strongly induced the nuclear translocation of
Smad2 , as well as other Smads