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ERBB3 — MAPK14

Text-mined interactions from Literome

Deb et al., J Biol Chem 2001 : K721M alone exhibited no detectable signaling capacity, whereas coexpression of K721M with ErbB2, but not ErbB3 or ErbB4, resulted in EGF dependent mitogen activated protein kinase ( MAPK ) activation
Vijapurkar et al., Exp Cell Res 2003 (Cell Transformation, Neoplastic...) : Roles of mitogen activated protein kinase and phosphoinositide 3'-kinase in ErbB2/ErbB3 coreceptor mediated heregulin signaling
Arnoletti et al., J Gastrointest Surg 2004 (Adenocarcinoma...) : Persistent MAPK activation and impaired in vitro internalization of EGFR by BxPC-3 pancreatic cancer cells may be due to constitutive ErbB3 signaling, facilitated by heterodimerization with EGFR, which may explain resistance to Erbitux based combination therapy in vivo
Benlimame et al., J Cell Biol 2005 (Cell Transformation, Neoplastic...) : ErbB induced oncogenic transformation correlates with the ability of FAK to restore ErbB-2/3 induced mitogen activated protein kinase ( MAPK ) activation ; the inhibition of MAPK prevented oncogenic transformation
Balko et al., Proc Natl Acad Sci U S A 2012 (MAP Kinase Signaling System) : We report here that ErbB3 loss in the luminal mammary epithelium of mice impaired Akt and MAPK signaling and reduced luminal cell proliferation and survival