Gene interactions and pathways from curated databases and text-mining

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PTGS2 — RP9

Text-mined interactions from Literome

Johnson et al., J Biol Chem 1999 : Inhibition of PAP-1 activity by three different strategies ( i.e. use of bromoenol lactone, propranolol, and ethanol ) resulted in inhibition of COX-2 expression and hence of PGE ( 2 ) production
Grkovich et al., J Biol Chem 2006 : Inhibition of PAP-1 by bromoenol lactone, propranolol, or ethanol resulted in a decrease in LPS induced COX-2 mRNA transcript production, COX-2 protein expression, and prostaglandin E ( 2 ) release from U937 macrophages
Miller et al., J Cell Biochem 1998 : 32P-AP-1 consensus sequence binding was unaffected by incubation of chondrocytes with KT-5720 or CalC, but was dramatically diminished by excess radioinert AP-1 and CRE-COX-2 oligos