Gene interactions and pathways from curated databases and text-mining

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HBEGF — OLR1

Text-mined interactions from Literome

Mukai et al., Atherosclerosis 2004 : HB-EGF induced expression of LOX-1 was suppressed by ZD1839, an inhibitor of EGF receptor phosphorylation ... Both MEK and p38 mitogen activated protein kinase ( MAPK ) inhibitors significantly blocked LOX-1 upregulation induced by HB-EGF ... Phosphatidylinositol 3-kinase (PI3K) inhibitors also blocked HB-EGF induced LOX-1 expression
Aramaki et al., Atherosclerosis 2008 (Atherosclerosis) : Inhibitors of metalloproteinases, epidermal growth factor (EGF) receptor tyrosine kinase, heparin binding EGF-like growth factor ( HB-EGF ), p38 mitogen activated protein kinase ( p38 MAPK ), MAPK kinase ( MEK1 ) and phosphoinositide 3-kinase (PI3K) significantly blocked RLP induced LOX-1 expression and cell migration of BVSMCs