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CDK9 — SUPT5H

Pathways - manually collected, often from reviews:

• Reactome Reaction: CDK9 → SUPT5H (indirect_complex) Shilatifard et al., Annu Rev Biochem 2003
• Reactome Reaction: CDK9 → SUPT5H (reaction)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: CDK9 — SUPT5H (direct interaction, enzymatic study) Larochelle et al., Nature structural & molecular biology 2012*
• IRef Biogrid Interaction: CDK9 — SUPT5H (direct interaction, pull down) Larochelle et al., Nature structural & molecular biology 2012*
• IRef Biogrid Interaction: CDK9 — SUPT5H (direct interaction, enzymatic study) Larochelle et al., Nature structural & molecular biology 2006
• IRef Biogrid Interaction: CDK9 — SUPT5H (direct interaction, enzymatic study) Michels et al., EMBO J 2004*
• IRef Biogrid Interaction: CDK9 — SUPT5H (direct interaction, enzymatic study) Garber et al., Mol Cell Biol 2000*
• IRef Biogrid Interaction: CDK9 — SUPT5H (direct interaction, pull down) Garber et al., Mol Cell Biol 2000*
• MIPS CORUM RNA pol II containing coactivator complex Tat-SF: RNA pol II containing coactivator complex Tat-SF complex (CDK9-HTATSF1-NCL-POLR2A-SUPT5H) Parada et al., EMBO J 1999
• MIPS CORUM Transcription elongation factor complex (SUPT5H, CDK9, CCNT1): Transcription elongation factor complex (SUPT5H, CDK9, CCNT1) complex (CCNT1-CDK9-SUPT5H) Kim et al., J Biol Chem 2001*
• IRef Corum Interaction: Complex of SUPT5H-CCNT1-CDK9 (association, far western blotting) Kim et al., J Biol Chem 2001*
• IRef Corum Interaction: Complex of 11 proteins (association, molecular sieving) Parada et al., EMBO J 1999
• IRef Dip Interaction: SUPT5H — CDK9 (direct interaction, protein kinase assay) Larochelle et al., Nature structural & molecular biology 2006
• IRef Hprd Interaction: Complex of SUPT5H-CCNT1-CDK9-CCNT1-SUPT5H-CDK9-CDK9-SUPT5H-CCNT1 (in vivo) Kim et al., J Biol Chem 2001*
• IRef Hprd Interaction: CDK9 — SUPT5H (in vitro) Kim et al., J Biol Chem 2001*, Lavoie et al., J Mol Biol 2001*
• IRef Hprd Interaction: Complex of 17 proteins (in vivo) Yik et al., Mol Cell 2003*

Text-mined interactions from Literome

Ping et al., J Biol Chem 2001 : DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation
Lavoie et al., J Mol Biol 2001 : Cdk9 dependent phosphorylation of Rpb1 and hSpt5 followed by Pin1 interaction might thus contribute to the regulation of transcription, pre-mRNA maturation, and the dynamics of these proteins in interphase and mitosis