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SIL1 — TP53

Text-mined interactions from Literome

Aubrecht et al., Carcinogenesis 1999 : Western blot analysis of embryos indicated that p53 protein levels increased approximately 3-fold following X-ray treatment, while B¿aP had no effect on p53 expression
Drukteinis et al., Placenta 2005 (Choriocarcinoma...) : Although BaP had no effect on total cellular p53 levels, phosphorylation of p53 at serine 15 ( p53 ser-15phos ) was markedly increased
Sadikovic et al., Toxicol Appl Pharmacol 2006 (Breast Neoplasms) : Furthermore, BaP increased p53 levels in both p53 positive cell lines, as well as p21 levels in MCF-7 cells, an effect that was prevented by the p53-specific inhibitor pifithrin-alpha
Huc et al., Cancer Res 2007 : This activation, in combination with BaP induced phosphorylated p53 , promoted mitochondrial superoxide anion production, supporting the existence of a common target for NHE1 and p53
Lin et al., Toxicology 2008 : BaP induced accumulation and activation of p53 in HepG ( 2 ) cells, which occurred as early as 12h after exposure
Huang et al., Toxicol Lett 2012 : Our data showed that Fla enhanced BaP induced p53 expression and promoted BaP induced cell death