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IL8 — MYLIP
Text-mined interactions from Literome
Stanczyk et al., Arthritis Rheum 2008
(Arthritis, Rheumatoid) :
Constitutive expression of both miR-155 and miR-146a was higher in RASFs than in those from patients with osteoarthritis ( OA ), and expression of
miR-155 could be further
induced by TNFalpha,
interleukin-1beta , lipopolysaccharide, poly ( I-C ), and bacterial lipoprotein
Xiao et al., J Infect Dis 2009
(Helicobacter Infections...) :
Furthermore, the overexpression of
miR-155 negatively
regulated the release of
interleukin-8 and growth related oncogene-alpha
Bhaumik et al., Aging 2009
:
Indeed, ectopic expression of
miR-146a/b in primary human fibroblasts
suppressed IL-6 and
IL-8 secretion and downregulated IRAK1, a crucial component of the IL-1 receptor signal transduction pathway
Larner-Svensson et al., Respir Res 2010
:
Functional studies indicated that IL-1beta induced
miR-146a expression does not negatively
regulate IL-6 and
IL-8 release or basal proliferation ... Unlike previous reports, studies using miRNA inhibitors showed that
miR-146a expression did not
regulate IL-6 and
IL-8 release or proliferation and suggest miR-146a function and mechanism is cell-type dependent
Majid et al., Cancer 2010
(Neoplasm Invasiveness...) :
In this study, the authors demonstrated that
miRNA-205 (miR-205) induced the expression the
interleukin ( IL ) tumor suppressor genes IL24 and IL32 by targeting specific sites in their promoters
Hu et al., J Biol Chem 2011
(Breast Neoplasms...) :
miR-520b regulates migration of breast cancer cells by targeting hepatitis B X-interacting protein and
interleukin-8 ... In addition, we found that
miR-520b could indirectly
regulate IL-8 transcription by targeting HBXIP ... Thus, we conclude that
miR-520b is
involved in regulating breast cancer cell migration by targeting HBXIP and
IL-8 via a network in which HBXIP promotes migration by stimulating NF-?B mediated IL-8 expression
Dai et al., Mol Hum Reprod 2012
(Endometriosis) :
Accompanied by IKKß reduction,
miR-199a suppressed nuclear factor-kappa B ( NF-?B ) pathway activation and
interleukin-8 (IL-8) production in ESCs
Xu et al., J Immunol 2013
(Psoriasis) :
Specific inhibition of
miR-31 suppressed NF-?B-driven promoter luciferase activity and the basal and TNF-a induced production of IL-1ß, CXCL1/growth related oncogene-a, CXCL5/epithelial derived neutrophil activating peptide 78, and
CXCL8/IL-8 in human primary keratinocytes
Tsuchiya et al., J Interferon Cytokine Res 2013
(Cystic Fibrosis...) :
However, whether infection induced
IL-8 expression in CF cells is also
mediated by
miR-155 is not known
Kuo et al., PloS one 2013
(Asthma...) :
This increase of
IL-8 secretion was
due to an elevated
microRNA-155 (miR-155) expression, which caused the suppression of Src homology 2 domain containing inositol 5-phosphatase 1 ( SHIP1 ) production and the subsequent activation of JNK signaling