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ADCY8 — ADORA1
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Kang et al., Neurosci Lett 2003
:
These results suggest that posterior hypothalamic
adenosine A ( 2 ) receptors play an inhibitory role in the central cardiovascular regulation and that both
adenylate cyclase and guanylate cyclase
mediate the depressor and bradycardiac actions of adenosine A ( 2 ) receptors
Keen et al., Biochim Biophys Acta 1992
:
Prostacyclin and
adenosine A2 receptors
stimulate adenylate cyclase activity in the related somatic hybrid cell lines NG108-15 and NCB20
de Carvalho et al., Brain Res Dev Brain Res 1992
:
Although
adenosine A1 receptors
mediate the inhibition of dopamine dependent stimulation of
adenylate cyclase activity in the developing chick retina, their localization and function are unknown
Kelly et al., Br J Pharmacol 1990
(Neuroblastoma) :
1. Prostacyclin and
adenosine A2 receptors
activate adenylate cyclase in the neuroblastoma hybrid cell lines NG108-15 and NCB-20
Coffey et al., J Leukoc Biol 1990
:
Desensitization was heterologous, since the
adenylate cyclase responses to 5'- ( N-ethylcarboxamido
) adenosine ( A2 receptor agonist ), isoproterenol ( beta-adrenoceptor agonist ), and prostaglandin E2 ( PGE2 ) also declined during culture
Wojcik et al., Neurosci Lett 1983
:
Stimulation of either
adenosine A1 or A2 receptors
results in a decrease or an increase in the
adenylate cyclase activity, respectively
Felsch et al., J Immunol 1995
:
This effect is possibly independent of
adenosine A2 receptor
mediated stimulation of
adenylate cyclase in neutrophils and cultured endothelial cells