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ETS2 — PARP1
Text-mined interactions from Literome
Soldatenkov et al., Oncogene 1999
(Sarcoma, Ewing) :
The
participation of
ETS in the regulation of
PARP gene expression was further demonstrated in EWS cells stably transfected with Ets1 antisense cDNA constructs ... These data provide support for
ETS regulation of
PARP expression levels, and implicate ETS transcription factors in the radiation response of EWS cells
Brenner et al., Cancer Cell 2011
(Neoplasm Invasiveness...) :
Importantly, pharmacological inhibition of
PARP1 inhibits
ETS positive, but not ETS negative, prostate cancer xenograft growth