Manna et al., J Biol Chem 2005
:
The data suggest that IL-8 induced NF-kappaB activation proceeds through a TRAF2 independent but TRAF6 dependent pathway, followed by recruitment of IRAK and activation of IKK Chang et al., Nat Immunol 2009
(Inflammation) :
Peli1 was required for TLR3 induced activation of IkappaB kinase (IKK) and its ` downstream ' target, transcription factor NF-kappaB, but was dispensable for IKK-NF-kappaB activation induced by several other TLRs and the interleukin 1 (IL-1) receptor