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IL1A — PAK1

Text-mined interactions from Literome

Zhou et al., BMC immunology 2009 : In response to TNF-alpha or IL-1alpha , PAK1 was promptly activated, as characterized by a sequential phosphorylation, initiated at threonine-212 followed by at threonine-423 in the activation loop of the kinase, in human skin keratinocytes, dermal fibroblasts, and rat hepatic stellate cells
Zhao et al., Journal of neuroinflammation 2011 (Wounds and Injuries) : Detailed analyses in cultured neurons and glial cells revealed that PAK1 mediated enhancement of IL-1RI activation is governed to a large extent by c-Src/miRNA222 signaling ; this signaling played a central role in the modulation of lymphocyte proliferation and NK cell activity