Akekawatchai et al., J Biol Chem 2005
(Breast Neoplasms...) :
Neither CXCR4 knockdown nor PTX had any effect on the ability of IGF-1 to activate IGF-1R, suggesting that CXCR4 and G proteins are activated subsequent to, or independently of, phosphorylation of IGF-1R by IGF-1 Li et al., Biochem Biophys Res Commun 2007
:
We isolated and cultured MSC from rat bone marrow, and found that IGF-1 increased the expression levels of the chemokine receptor CXCR4 ( receptor for stromal cell derived factor-1, SDF-1 )
Sinha et al., Cell Signal 2011
(Glioblastoma...) :
Importantly, TLR9 agonist reversed the effect of IGF-1 on CXCR4 and SOCS3 expression