UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to CTNND1

CTNND1 — PVRL2

Pathways - manually collected, often from reviews:

NCI Pathway Database Stabilization and expansion of the E-cadherin adherens junction: nectin-2(dimer)/I-afadin/I-afadin/nectin-2(dimer/I-afadin/I-afadin complex (PVRL2-MLLT4) → E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin complex (CDH1-CTNNB1-CTNNA1-CTNND1) (translocation, activates)
Yeaman et al., J Cell Sci 2004, Nejsum et al., J Cell Biol 2007
Evidence: mutant phenotype, physical interaction