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CDKN1A — RHOB

Text-mined interactions from Literome

Du et al., Mol Cell Biol 1999 : In support of this hypothesis, when expressed in Ras transformed cells RhoB-GG induced phenotypic reversion, cell growth inhibition, and activation of the cell cycle kinase inhibitor p21WAF1
Du et al., Cancer Res 1999 (Neoplasms, Glandular and Epithelial) : RhoB-GG induced the cell cycle kinase inhibitor p21 ( WAF1 ) in a p53 dependent manner, similar to FTI treatment, but this event was dispensable because RhoB-GG could still inhibit the growth of p53-null cells that lacked p21WAF1 activation
Marlow et al., Cancer Res 2009 (Carcinoma...) : Using multiple independently derived ATC cell lines, we found that treatment with RS5444 leads to the up-regulation of RhoB and subsequent activation of p21 , and that silencing of RhoB by RNAi blocks the ability of RS5444 to induce p21 and to inhibit cell proliferation