Gene interactions and pathways from curated databases and text-mining

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LEP — LIFR

Text-mined interactions from Literome

Gonzalez et al., Endocrinology 2004 : Interestingly, the inhibition of IL-1R tI with a specific antibody or with IL-1Ra negatively affects both leptin induced and IL-1 induced effects on LIF-R levels
Nakashima et al., FEBS Lett 1997 : Since the IL-6 family of cytokines signal through gp130 homodimer or gp130/LIFR heterodimer, we have examined in this study the possible involvement of gp130 and LIFR in leptin signaling through OB-R ... Leptin stimulation induces tyrosine phosphorylation of neither gp130 nor LIFR , while LIF stimulation does both