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RAD50 — RAF1

Text-mined interactions from Literome

Schmitt et al., Mol Cell Biol 2001 : Activation of Rap1 by cAMP induces the association of Rap1 with Raf-1 and limits Ras dependent activation of ERK
Lee et al., J Cell Biochem 2007 : However, in the presence of Raf-1, an interaction between Rad24 and Cdc25 was inhibited in triple hybrid assay, indicating that Raf-1 inhibits the interaction between Rad24 and Cdc25
Vossler et al., Cell 1997 : Rap1 , activated by mutation or by the cAMP dependent protein kinase PKA, is a selective activator of B-Raf and an inhibitor of Raf-1
Hu et al., J Biol Chem 1997 : However, Rap1A , which has an identical effector domain to that of Ras, can not activate Raf-1 and even antagonizes several Ras functions in vivo
Hu et al., J Biol Chem 1999 : Effect of phosphorylation on activities of Rap1A to interact with Raf-1 and to suppress Ras dependent Raf-1 activation