Gene interactions and pathways from curated databases and text-mining

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EPHB2 — MPL

Text-mined interactions from Literome

Martin et al., Infect Immun 2003 : Analysis of MPL induced activation of the extracellular signal regulated kinase ( ERK ) and p38 mitogen activated protein ( MAP ) kinases revealed that MPL utilized both TLR2 and TLR4 for the phosphorylation of ERK1/2, while TLR4 was the predominant receptor involved in the ability of MPL to phosphorylate p38
Sohn et al., Chest 2005 (Pneumonia) : These observations suggest that activation of ERK by MPL may be one of the mechanisms that result in an increase of the production of IL-8
Rodriguez et al., Eukaryotic cell 2008 : MPL1 , a novel phosphatase with leucine-rich repeats, is essential for proper ERK2 phosphorylation and cell motility