Semplicini et al., J Hypertens 2006
(Hypertension) :
Reduced expression of regulator of G-protein signaling 2 ( RGS2 ) in hypertensive patients increases calcium mobilization and ERK1/2 phosphorylation induced by angiotensin II
Jin et al., J Biol Chem 2009
:
Vascular endothelial growth factor ( VEGF ), which is regulated by HIF-1, did not appear to be involved in hypoxia induced RGS5 expression ; however, VEGF mediated activation of p38 but not ERK1/2 was increased by RGS5 Koh et al., Mol Endocrinol 2011
(Adenoma...) :
Transient expression of RGS5 in cells stably expressing CaSR resulted in dose dependent abrogation of calcium stimulated inositol trisphosphate production and ERK1/2 phosphorylation