Gene interactions and pathways from curated databases and text-mining

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ADAMTS5 — IL1A

Text-mined interactions from Literome

Imada et al., Biochem Biophys Res Commun 2008 (Arthritis, Experimental) : Nobiletin ( 16-64muM ) interfered with the interleukin (IL)-1beta mediated ADAMTS-4 and -5 mRNA expression in cultured human synovial fibroblasts
Ellman et al., Gene 2012 (Intervertebral Disc Degeneration) : In bovine NP cells, MyD88i potently antagonizes LPS- or IL-1 mediated induction of cartilage degrading enzyme production, including MMP-1, MMP-13, ADAMTS-4, and ADAMTS-5
Sylvester et al., Cell Physiol Biochem 2012 : C-Jun N-terminal kinase (JNK) inhibitor, SP600125 diminished IL-1 stimulated JNK phosphorylation, ADAMTS-4 mRNA expression and enzyme activity
Wei et al., Spine (Phila Pa 1976) 2013 : Gene expression of ADAMTS-4, ADAMTS-5 , and TGF-b were not affected by IL-1 or ERK inhibition ... Gene expression of ADAMTS-4, ADAMTS-5 , and TGF-b were not affected by IL-1 or ERK inhibition