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COMP — IL1A

Text-mined interactions from Literome

Dickinson et al., Matrix Biol 2003 : In this study we utilised well established bovine cartilage culture models to examine IL-1alpha stimulated COMP proteolysis in the presence and absence of MMP inhibitors ... COMP was released from bovine nasal cartilage, in response to IL-1alpha , at an intermediate time between proteoglycans and type II collagen, when soluble MMP levels in the culture medium were undetectable
Ganu et al., Arthritis Rheum 1998 (Arthritis...) : Inhibition of interleukin-1alpha induced cartilage oligomeric matrix protein degradation in bovine articular cartilage by matrix metalloproteinase inhibitors : potential role for matrix metalloproteinases in the generation of cartilage oligomeric matrix protein fragments in arthritic synovial fluid