Heal et al., Mol Immunol 1999
:
A best-fit peptide corresponding to this motif was synthesised and found to bind to IL-1beta as well as inhibit the response to IL-1 in two independent in vitro bioassays ( monitoring IL-1 dependent serum amyloid A synthesis and IL-1 dependent alkaline phosphatase activity, respectively )
Kumon et al., Scand J Immunol 2001
(Acute-Phase Reaction...) :
Dexamethasone, but not IL-1 alone, upregulates acute-phase serum amyloid A gene expression and production by cultured human aortic smooth muscle cells
Ghezzi et al., Lymphokine Res 1988
:
Dexamethasone modulation of LPS, IL-1 , and TNF stimulated serum amyloid A synthesis in mice
Kumon et al., Scand J Immunol 1997
:
Regulation of extrahepatic apolipoprotein serum amyloid A ( ApoSAA ) gene expression by interleukin-1 alpha alone : synthesis and secretion of ApoSAA by cultured aortic smooth muscle cells