Gene interactions and pathways from curated databases and text-mining

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IL1R1 — IL2

Text-mined interactions from Literome

Yuan et al., Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2002 (Disease Models, Animal) : [ Effect of interleukin-1 on expression of interleukin-1 receptor in KM mice sciatic nerves before and after injuries ]
Liberman et al., Eur J Immunol 1992 : Our binding and functional studies strongly support the hypothesis that high-affinity IL-1R on the one hand, and low-affinity ones on the other hand, are involved in the response to IL-1 + IL-2 of newborn and day 17.5 fetal thymocytes, respectively
Dahlén et al., J Immunotoxicol 2008 (Arthritis, Experimental) : Interleukin-1 receptor antagonist ( IL-1Ra ) is a naturally occurring inhibitor of the pro-inflammatory interleukin-1 mediated activation of the interleukin-1 receptor (IL-1R)
Shemesh et al., Atherosclerosis 2012 (Aortic Diseases...) : Interleukin-1 receptor type-1 in non-hematopoietic cells is the target for the pro-atherogenic effects of interleukin-1 in apoE-deficient mice
Shirakawa et al., J Immunol 1987 : Furthermore the binding of 125I labeled IL 1 alpha to IL 1R on T cells was inhibited by the addition of either cold IL 1 alpha or IL beta, but not by interleukin 2 or interferons
Bonin et al., J Biol Chem 1988 : Modulation of interleukin-1 receptor expression and interleukin-1 response in fibroblasts by platelet derived growth factor
Heguy et al., J Biol Chem 1993 : A chimeric type II/type I interleukin-1 receptor can mediate interleukin-1 induction of gene expression in T cells