◀ Back to IL2

IL2 — KLRC1

Text-mined interactions from Literome

Seo et al., Clin Exp Immunol 2000 (Epstein-Barr Virus Infections...) : Freshly isolated leukaemic NK cells transcribed mRNA for CD94 associated molecule NKG2C at an abnormally high level, and upon stimulation with IL-2 and/or IL-12 they expressed NKG2A as well
Li et al., Cancer Res 2002 (Carcinoma, Squamous Cell...) : Interleukin 2 gene transfer prevents NKG2D suppression and enhances antitumor efficacy in combination with cisplatin for head and neck squamous cell cancer
Koike et al., J Exp Med 2004 : Furthermore, anti-NKG2I mAb inhibited NK cell mediated cytotoxicity, whereas cross linking of NKG2I enhanced interleukin 2- and interleukin 12-dependent interferon-gamma production
Burgess et al., J Immunol 2006 : We report that culture of human primary NK and CD8+ T cells with IL-21 in combination with IL-2 results in significant reduction of the cell surface expression of NKG2D , compared with that in cells treated with IL-2 alone
Lilienfeld et al., J Immunol 2006 : Human NK cytotoxicity against pEC mediated by freshly isolated or IL-2 activated NK cells through NKG2D was completely blocked using anti-pULBP1 polyclonal Ab
Song et al., Cell Immunol 2006 : In this study, we observed that IL-2/IL-18 increased the NKG2D expression in the TGF-beta treated NK cell line in a dose dependent manner ... Incubation with the JNK inhibitor SP600125 inhibited the NKG2D expression induced by IL-2/IL-18 in the TGF-beta treated human NK cell line ... The results indicate that IL-2/IL-18 strongly prevented the TGF-beta induced NKG2D down-regulation in NK cells via the JNK pathway
Huang et al., Oncol Rep 2010 : Up-regulation of NKG2F receptor, a functionally unknown killer receptor, of human natural killer cells by interleukin-2 and interleukin-15
Wang et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2012 : The expression of CD62L was not changed statistically after stimulation with cytokines, the IL-2 down-regulated the expressions of NKG2A and NCR46, while IL-15 showed the opposite effect
Hromadnikova et al., Mediators Inflamm 2013 : Using flow cytometry the effect of in vitro stimulation with IL-2 or IL-15 alone or in combination with Hsp70 derived 14-mer peptide ( TKD ) on cell surface expression of NK activatory receptors ( CD16, NKG2D, NKG2C , NKp46, NKp44, NKp30, KIR2DL4, DNAM-1, and LAMP1 ) and NK inhibitory receptors ( NKG2A, KIR2DL2/L3, LIR1/ILT-2, and NKR-P1A ) in healthy individuals was studied
Glässner et al., J Hepatol 2013 (Coinfection...) : Here, we show that CD4 ( + ) T cells are able to stimulate anti-fibrotic NK cell activity via IL-2 mediated upregulation of NKG2D