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ALOX12 — SP1

Text-mined interactions from Literome

Chang et al., Prostaglandins Other Lipid Mediat 2003 : The direct and cooperative interaction between c-Jun and Sp1 induced by EGF or PMA activates the expression of the human 12(S)-lipoxygenase gene
Chang et al., Biochem Biophys Res Commun 2005 : In addition to the functional role of Sp1 in gene regulation of 12(S)-lipoxygenase , recent studies have also demonstrated that Sp1 acting as an anchor protein to recruit transcription factor c-Jun is essential for growth factor and/or phorbol ester induced expression of several genes