Gene interactions and pathways from curated databases and text-mining

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ANGPT2 — LEP

Text-mined interactions from Literome

Cohen et al., J Biol Chem 2001 : Leptin induces angiopoietin-2 expression in adipose tissues ... We demonstrate that leptin induces the expression of Ang-2 in adipose tissue without a concomitant increase in VEGF ... We propose that induction of Ang-2 by leptin in adipose cells is one of the events leading to adipose tissue regression
Kim et al., J Nutr 2002 : In conclusion, although Ang II stimulates both leptin and PG secretion by adipocytes, regulation of leptin secretion by Ang II in adipocytes is not mediated by a PG-dependent mechanism
Skurk et al., Obes Res 2005 (MAP Kinase Signaling System) : Here we tested whether angiotensin (Ang) II is involved in the control of leptin release from human adipocytes
Shyu et al., Clin Sci (Lond) 2012 : In conclusion, Ang II induces leptin expression in human VSMCs, and atorvastatin could inhibit the leptin expression induced by Ang II