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BCL2 — PDCD2

Text-mined interactions from Literome

Korsmeyer et al., Cancer Res 1999 (Hyperplasia...) : BCL-2 gene family and the regulation of programmed cell death
Dilla et al., Endocrinology 2000 (Carcinoma, Medullary...) : MDM2 mediated programmed cell death is at least mediated by a down-regulation of the antiapoptotic protein Bcl-2
Hamzaoui et al., Mediators Inflamm 1999 (Behcet Syndrome...) : Defective regulation of programmed cell death ( apoptosis ) may play a role in the development of ( BD ), and the proto-oncogene Bcl-2 is involved in the control of apoptosis in immunocompetent cells
Koty et al., Lung Cancer 2002 (Carcinoma, Non-Small-Cell Lung...) : In vivo expression of p53 and Bcl-2 and their role in programmed cell death in premalignant and malignant lung lesions
Ottaviani et al., Cell Biol Int 2002 : BCL-2 does not control programmed cell death in the IPLB-LdFB cell line from the insect Lymantria dispar
Munger et al., Virology 2003 : The programmed cell death induced by this mutant is blocked by overexpression of Bcl-2 or by transduction of infected cells with the gene encoding the viral U ( S ) 3 protein kinase
Vogel et al., Cerebellum 2002 : The purpose of this review is to summarize recent findings about the role of Bcl-2 and Bax in regulating programmed cell death in the cerebellum during normal development and in a mouse model of cell autonomous and target related cell death, the Lurcher mutant
Pinto et al., J Comput Aided Mol Des 2004 : Overexpression of Bcl-2 and Bcl-xL proteins, both inhibitors of apoptosis or programmed cell death , is related to the generation and development of several types of cancer as well as to an elevated resistance to chemotherapeutic treatments ... Overexpression of Bcl-2 and Bcl-xL proteins, both inhibitors of apoptosis or programmed cell death , is related to the generation and development of several types of cancer as well as to an elevated resistance to chemotherapeutic treatments
Hu et al., Clin Cancer Res 2004 (Carcinoma, Non-Small-Cell Lung...) : Overexpression of Bcl-2 protein in cancer cells can inhibit programmed cell death and engender chemoresistance
Peterson et al., Hybridoma (Larchmt) 2005 : Annexin staining in hybridoma 7.16.4 confirmed that apoptosis was the primary means of cell death in this cell line, and expression of Bcl-2-delta and Bcl-xl-delta inhibited programmed cell death
Thuduppathy et al., Protein Sci 2006 : Regulation of programmed cell death by Bcl-xL is dependent on both its solution and integral membrane conformations
Boehm et al., Curr Mol Med 2006 (Skin Diseases) : Experimental evidence suggests a role for Bcl-2 and CD95L in the inhibition of programmed cell death in UV-induced skin cancer or malignant melanoma cells
Schäbitz et al., J Cereb Blood Flow Metab 2008 (Brain Infarction...) : In primary cortical neurons and human neuroblastoma cells, GM-CSF counteracts programmed cell death and induces BCL-2 and BCL-Xl expression in a dose- and time dependent manner ... In primary cortical neurons and human neuroblastoma cells, GM-CSF counteracts programmed cell death and induces BCL-2 and BCL-Xl expression in a dose- and time dependent manner
Nuñez et al., Nature 1991 : Bcl-2 , an inner mitochondrial membrane protein, blocks programmed cell death in B cells
Huang et al., Curr Opin Drug Discov Devel 2000 : Bcl-2 and related proteins play a central role in the regulation of programmed cell death or apoptosis implicated in many human diseases
Chand et al., J Immunol 2012 (Chronic Disease...) : Bcl-2 , a prosurvival protein, regulates programmed cell death during development and repair processes, and it can be oncogenic when cell proliferation is deregulated
Krajewski et al., Am J Pathol 1995 : The mcl-1 gene encodes an approximately 37-kd protein that has significant homology with Bcl-2 , an inhibitor of programmed cell death that is expressed in many types of long lived cells
Schena et al., Leukemia & lymphoma 1993 (Leukemia, Lymphocytic, Chronic, B-Cell) : The Bcl-2 gene product regulates programmed cell death and a number of experiments suggest that Bcl-2 is involved in the selection and maintenance of long lived memory B cells rescuing them from apoptotic death and leading to their accumulation in the GO phase of the cell cycle
Park et al., J Acquir Immune Defic Syndr Hum Retrovirol 1996 : Effects of human immunodeficiency virus type 1 infection on programmed cell death in the presence or absence of Bcl-2
Papadimitriou et al., Eur J Cancer 1997 (Breast Neoplasms...) : The Bcl-2 gene product prevents programmed cell death ( apoptosis ) and possibly promotes tumour development
Li et al., J Biol Chem 1997 : Bcl-xL , an antiapoptotic member of the Bcl-2 family, inhibits programmed cell death in a broad variety of cell types
Sheng et al., Cancer Res 1998 (Colonic Neoplasms...) : Additionally, PGE2 inhibits programmed cell death caused by SC-58125 and induces Bcl-2 expression, but did not affect Bcl-x or Bax expression in human colon cancer ( HCA-7 ) cells
Weinstein et al., Oncogene 1998 (Breast Neoplasms) : Conversely, the transfection of Bcl-2 into MCF-7 cells inhibits heregulin mediated programmed cell death