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CXCL12 — MMP3

Text-mined interactions from Literome

Yu et al., J Bone Miner Res 2003 (Bone Resorption) : SDF-1 versus RANKL effects on chemotaxis, transcollagen migration, MMP-9 expression and activity, OC development, and bone resorption were evaluated in RAW cells or RAW-OCs
Ries et al., Blood 2007 (Inflammation) : Moreover, the inflammatory cytokines TGF-beta1, IL-1beta, and TNF-alpha up-regulated MMP-2, MT1-MMP, and/or MMP-9 production in these cells, resulting in a strong stimulation of chemotactic migration through ECM, whereas the chemokine SDF-1alpha exhibited minor effects on MMP/TIMP expression and cell invasion
Laird et al., Hum Reprod 2011 : Expression of CXCL12 and CXCR4 in human endometrium ; effects of CXCL12 on MMP production by human endometrial cells ... The aim of this study was to investigate CXCL12 and CXCR4 expression in human endometrium and to see if CXCL12 could affect matrix metalloproteinase ( MMP ) production by endometrial stromal and epithelial cells
Li et al., Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2012 (Osteoarthritis) : SDF-1 could induce overexpression and release of MMP-3 , 9, and 13 in the articular cartilage through the SDF-1/CXCR4 signaling pathway ; AMD3100 could reduce the mRNA expressions and secretion of MMP-3, 9, and 13 in OA cartilage by blocking the SDF-1/CXCR4 signaling pathway ; but AMD3100 could not make the secretion of MMP-3, 9, and 13 return to normal levels in OA cartilage