Pedraza-Alva et al., EMBO J 2006
:
Active p38 MAP kinase promotes a G2/M cell cycle checkpoint through the phosphorylation and activation of p53 in these cells in vivo
Wu et al., PloS one 2012
(Neoplasms) :
However, the general biochemical functions of AGR2 in human cells remain undefined, and the signaling mechanisms that drive AGR2 to inhibit p53 are still not clearly illustrated