Gene interactions and pathways from curated databases and text-mining

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LEP — SOD1

Text-mined interactions from Literome

Zwirska-Korczala et al., J Physiol Pharmacol 2007 : Leptin and ghrelin increased activity of SOD , CAT, GSH-Px and decreased level of MDA
Guo et al., J Biol Chem 2008 (Seizures) : Leptin induces the production of manganese superoxide dismutase and the anti-apoptotic protein Bcl-xL, and stabilizes mitochondrial membrane potential and lessens mitochondrial oxidative stress
Motawi et al., J Biomed Sci 2008 : Leptin significantly increased mucin and tissue NO, restored GR and SOD activities and up-regulated GPx activity
Chetboun et al., J Cell Biochem 2012 : Both leptin and adiponectin reduced mRNA levels of superoxide dismutase (SOD)1