NCI Pathway Database Direct p53 effectors:
PUMA/BCL2 subfamily complex (BBC3-BCL2_MCL1_BCL2L2_BCL2A1_BCL2L1)
→
p53/BCL2 subfamily complex (TP53-BCL2_MCL1_BCL2L2_BCL2A1_BCL2L1)
(modification, collaborate)
Chipuk et al., Science 2005 Evidence: mutant phenotype, physical interaction, other species
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
MIPS Negatome - no physical interaction between proteins Interaction:
MCL1
—
BCL2L2, BCL2L2-PABPN1
(Absence of interaction, two hybrid)
Bae et al., J Biol Chem 2000*