Gene interactions and pathways from curated databases and text-mining

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HIF1A — MMP9

Text-mined interactions from Literome

Luo et al., BJU Int 2006 (Neoplasm Invasiveness...) : The expression of E-cadherin, vimentin, cathepsin D, MMP-2 and uPAR, which are proteins with established roles in the pathophysiology of invasion, could be regulated by HIF-1alpha in human prostate cancer cells
Ding et al., Brain Res 2009 (Brain Injuries) : Inhibition of HIF-1alpha reduced expression of MMP-2 and -9
Kang et al., Clin Exp Pharmacol Physiol 2009 (Diabetes Mellitus, Experimental...) : Impairment of ischaemia induced EPC mobilization in the diabetic mouse model is associated with altered HIF-1 alpha/VEGF and MMP/TIMP regulation and represents a novel mechanism underlying defective postischaemic neovascularization in diabetes
Lee et al., J Cell Physiol 2010 : Consequently, the increased HIF-1alpha expression induced activation of matrix metalloproteinase (MMP)-2 and MMP-9