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CXCL1 — TLR2

Text-mined interactions from Literome

Hung et al., Nephrol Dial Transplant 2006 : The LMPS enhanced the secretion of CCL2/MCP-1 and CXCL8/interleukin-8 (CXCL8/IL-8) in TLR-defective human embryonic kidney (HEK) 293 cells only when transfected with a TLR2 expressing plasmid
Bsibsi et al., Glia 2007 : Moreover, the CD14 triggered TLR2 mediated response in astrocytes lead to the production of CXCL8 , IL-6, and IL12p40, whereas typical TLR induced pro-inflammatory cytokines, like TNF-alpha and IL-1beta, were not produced at detectable levels
Méndez-Samperio et al., Arch Med Res 2008 : Moreover, it is important to note that the levels of CXCL8 secretion and mRNA were markedly ( 94 % ) reduced by functional blocking of both TLR2 and TLR4
Wang et al., Blood 2008 : We and others have reported that Toll-like receptor ( TLR ) proteins are present on human neutrophils and that granulocyte-macrophage colony stimulating factor ( GM-CSF ) treatment enhances IL-8 ( CXCL8 ) secretion in response to stimulation with TLR ligands
Lee et al., J Clin Immunol 2009 : These results indicate that TLR2-ROS signaling plays a crucial role in the 30-kDa Ag-mediated expression of CXCL8 and CCL2 in human monocytes
Lee et al., Cell Microbiol 2009 : In addition, TLR2 , Dectin-1 and, to an extent, TLR4 are essential for the MU-mediated expression of CXCL8 , CCL2 and LL-37 in keratinocytes ... In addition, TLR2 , Dectin-1 and, to an extent, TLR4 are essential for the MU-mediated expression of CXCL8 , CCL2 and LL-37 in keratinocytes
Mersmann et al., Crit Care Med 2010 (Myocardial Infarction...) : In HL-1 cells, TLR2 activation amplified the expression of the receptor in a time dependent manner and led to CXCL1 release in a concentration dependent manner
Farges et al., Immunobiology 2011 : We found that odontoblasts produce the pro-inflammatory cytokines interleukin (IL)-6 and CXCL8 , as well as the immunosuppressive cytokine IL-10 in response to TLR2 agonists
Guerrero et al., Eur J Pharmacol 2012 : Moreover, the joint production of TNF-a, IL-1ß and CXCL1/KC by zymosan was dependent on TLR2/MyD88 signaling
Nischalke et al., J Hepatol 2012 (Disease Progression...) : The CXCL1 rs4074 A allele is associated with enhanced CXCL1 responses to TLR2 ligands and predisposes to cirrhosis in HCV genotype 1-infected Caucasian patients ... In vitro carriers of the A allele produced greater amounts of CXCL1 in response to TLR2-ligands including HCV core and NS3, and HCV infected carriers of the CXCL1 rs4074 A allele had higher CXCL1 serum levels than those with the G/G genotype
Oarada et al., J Nutr Biochem 2013 (Inflammation) : TLR2 deficiency significantly attenuated the refeeding induced increase in the liver expression of Cxcl10, Cxcl1 , Icam-1 and A20
Sharma et al., J Leukoc Biol 2013 : Our findings reveal a previously unrecognized role for S1P in regulating TLR induced CXCL8 secretion from human T cells