Kim et al., Invest Ophthalmol Vis Sci 2005
:
To evaluate the effects of TGF-beta1 and doxycycline on production of gelatinase MMP-9 and activation of Smad , c-Jun N-terminal kinase (JNK), extracellular regulated kinase (ERK), and p38 mitogen activated protein kinase ( MAPK ) signaling pathways in human corneal epithelial cells
Wiercinska et al., Breast Cancer Res Treat 2011
(Breast Neoplasms...) :
In line with this, TGF-ß was found to strongly induce MMP2 and MMP9 expression in a Smad3- and Smad4 dependent manner
Xu et al., Angiogenesis 2012
(Choroidal Neovascularization) :
The inhibition of MMP-9 was Smad dependent because BMP4 failed to repress TNF induced MMP-9 expression when Smad1,5 was silenced by siRNA