Gene interactions and pathways from curated databases and text-mining

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CPT2 — LEP

Text-mined interactions from Literome

Yamagishi et al., J Biol Chem 2001 : Leptin induced ROS generation, CPT-1 activation , ACC inhibition, and MCP-1 overproduction were found to be completely prevented by either genistein, a tyrosine kinase inhibitor, H-89, a protein kinase A (PKA) inhibitor, or tetradecylglycidate, a CPT-1 inhibitor
Luo et al., Mol Cell Biochem 2008 : Furthermore, at the level of 10 and 100 ng/ml leptin not only selectively increased the gene expression of PGC-1alpha, CPT1 , Cyt c, UCP2, and UCP3 ( P < 0.05 ), but also enhanced COX enzyme activity which related to mitochondrial FAO