Gene interactions and pathways from curated databases and text-mining

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COL4A2 — MMP15

Text-mined interactions from Literome

Ahmed et al., J Cell Biochem 2002 (Ovarian Neoplasms) : Plasminogen dependent [ 3H ] -collagen IV degradation was inhibited by inhibitor of uPA ( amiloride ) and MMP ( phenanthroline ) and by antibodies against uPA or MMP-9 or alphavbeta6 integrin, indicating the involvement of alphavbeta6 integrin, uPA and MMP-9 in the process
Altincicek et al., Dev Comp Immunol 2008 : Recently, we postulated that an endogenous MMP expressed in the lepidopteran model Galleria mellonella during metamorphosis causes degradation of collagen-IV , which in turn results in activation of innate immunity
Rebustini et al., Dev Cell 2009 : Specifically, reducing epithelial MT2-MMP profoundly decreases proliferation and morphogenesis, increases Col4a2 and intracellular accumulation of collagen IV, and decreases the proteolytic release of collagen IV NC1 domains